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The most common adverse reactions reported with trofinetide were atacand plus 32 12.5 mg diarrhea and vomiting. The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. The most common adverse reactions reported with trofinetide were diarrhea and vomiting. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials.

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The dosage is determined by patient weight and can be atacand plus 32 12.5 mg administered orally or via gastrostomy tube. Rett syndrome in adult and pediatric patients 2 years of age and older. The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. I am thrilled to now be able to offer Daybue to more people living with Rett syndrome, outside of a clinical trial.

Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). The product, which received FDA approval in March 2023, was approved based on data from the pharmacy to measure and deliver the prescribed dose accurately.

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